Via degli Dei crosses the Apennines between Bologna and Firenze, shifting from city streets to shaded forests and breezy ridges, with frequent transitions in exposure and footing. May and October align with cooler air for ascents, longer daylight, and lively spring or autumn scenery, with less heat and thunderstorm risk than midsummer. Weather changes quickly along the route, with passing showers, slick clay after rain, and noticeably cooler conditions on higher ground compared to the valleys.